MolNFT v1 · #52939 · protein
Crystal structure of the N-terminal signalling domain of human dhh without calcium
2WFQ · Desert hedgehog protein N-product: “Crystal structure of the N-terminal signalling domain of human dhh without calcium”. X-ray diffraction, 2 ligands (ZN, SO4), 1 pocket (best druggability 0.31). MolNFT v1 #52939 on GenesisL1: 3D…
- PDB
- 2WFQ
- Type
- protein
- Length
- 164 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Desert hedgehog protein N-product
- UniProt
- O43323
- Ligands
- ZN, SO4
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Desert hedgehog protein N-product | protein | 164 | 30% helix, 19% strand | O43323 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.31 | 0.75 | 15 | empty |
Compared structures
- 2WFQ · Crystal structure of the N-terminal signalling domain of human Dhh without calcium · the same entry in another collection · chain A against A, TM-score 1.00
- O43323 · AlphaFold monomer V2.0 prediction for desert hedgehog protein (O43323) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43323
- Elsewhere: RCSB PDB 2WFQ · PDBe 2WFQ · UniProt O43323
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