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SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF

Analyse SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QZH
Type: protein
Length: 129 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 14.0
Source: Homo sapiens
Molecule: Complement decay-accelerating factor
UniProt: P08174
Pockets: 2 · best druggability 0.50

Structure

electron microscopy · resolution 14.0 · 1 distinct chain · 0% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Complement decay-accelerating factor	protein	129	0% helix, 28% strand	P08174

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	271	0.50	0.75	48	empty
2	166	0.41	0.74	43	empty

Compared structures

2QZH · SCR2/3 of daf from the NMR structure 1NWV fitted into a cryoem reconstruction of CVB3-rd… · the same entry in another collection · chain A against A, TM-score 1.00
P08174 · AlphaFold monomer V2.0 prediction for complement decay-accelerating factor (P08174) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08174
Elsewhere: RCSB PDB 2QZH · PDBe 2QZH · UniProt P08174

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