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Structure of the transmembrane domain of human nicastrin in DPC micelles

Analyse Structure of the transmembrane domain of human nicastrin in DPC micelles in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2N7R
Type
protein
Length
46 residues
Chains
1
Method
solution nmr
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
NOT
Source
Homo sapiens
Molecule
Nicastrin
UniProt
Q92542

Structure

solution nmr · resolution NOT · 1 distinct chain · 67% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANicastrinprotein4667% helix, 0% strandQ92542

Compared structures

  • 2N7R · Structure of the transmembrane domain of human nicastrin in dpc micelles · the same entry in another collection · chain A against A, TM-score 1.00
  • Q92542 · AlphaFold monomer V2.0 prediction for nicastrin (Q92542) · a predicted model of the same protein · chain A against A, TM-score 0.66

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