Research workbench

YAP WW2 in complex with a Smad7 derived peptide

Analyse YAP WW2 in complex with a Smad7 derived peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LTV
Type: protein
Length: 48 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Homo sapiens; SYNTHETIC CONSTRUCT
Molecule: Yorkie homolog; Smad7 derived peptide
UniProt: P46937, O15105

Structure

solution nmr · resolution NOT · 2 distinct chains · 0% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Yorkie homolog	protein	36	0% helix, 42% strand	P46937
B	Smad7 derived peptide	protein	12	0% helix, 0% strand	O15105

Interfaces

1 interface between chains.

A–B · 529 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

2LTV · Yap WW2 in complex with a SMAD7 derived peptide · the same entry in another collection · chain A against A, TM-score 1.00
P46937 · AlphaFold monomer V2.0 prediction for transcriptional coactivator YAP1 (P46937) · a predicted model of the same protein · chain A against A, TM-score 0.63
O15105 · AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 7 (O15105) · a predicted model of the same protein · chain B against A, TM-score 0.36

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46937
Every structure of UniProt O15105
Elsewhere: RCSB PDB 2LTV · PDBe 2LTV · UniProt P46937 · UniProt O15105

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