Research workbench

Human interleukin-6, NMR, 32 structures

Analyse Human interleukin-6, NMR, 32 structures in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2IL6
Type: protein
Length: 166 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Homo sapiens
Molecule: Interleukin-6
UniProt: P05231
Pockets: 1 · best druggability 0.43

Structure

solution nmr · resolution NOT · 1 distinct chain · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interleukin-6	protein	166	63% helix, 0% strand	P05231

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	120	0.43	0.77	13	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2IL6 · Human interleukin-6, NMR, 32 structures · the same entry in another collection · chain A against A, TM-score 1.00
P05231 · AlphaFold monomer V2.0 prediction for interleukin-6 (P05231) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05231
Elsewhere: RCSB PDB 2IL6 · PDBe 2IL6 · UniProt P05231

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.