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Solution structure of the HRDC domain of human Exosome component 10

Analyse Solution structure of the HRDC domain of human Exosome component 10 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CPR
Type: protein
Length: 124 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Homo sapiens
Molecule: Exosome component 10
UniProt: Q01780
Pockets: 1 · best druggability 0.32

Structure

solution nmr · resolution NOT · 1 distinct chain · 45% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exosome component 10	protein	124	45% helix, 0% strand	Q01780

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.32	0.75	12	empty

Compared structures

2CPR · Solution structure of the hrdc domain of human exosome component 10 · the same entry in another collection · chain A against A, TM-score 1.00
Q01780 · AlphaFold monomer V2.0 prediction for exosome component 10 (Q01780) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01780
Elsewhere: RCSB PDB 2CPR · PDBe 2CPR · UniProt Q01780

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