UniProt Q01780
Exosome component 10 (Q01780)
Exosome component 10 (UniProt Q01780), EC 3.1.13.-: 12 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01780
- Protein
- Exosome component 10
- EC
- 3.1.13.-
- Experimental structures
- 12
- Predicted models
- 1
Structures
13 records of Q01780 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CPR | Solution structure of the HRDC domain of human Exosome component 10 | solution nmr | A | — | — |
| 2CPR | Solution structure of the hrdc domain of human exosome component 10 | solution nmr | A | — | — |
| 3SAF | Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site | x-ray diffraction | A, B | — | — |
| 3SAF | Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site | x-ray diffraction | A, B | — | — |
| 3SAG | Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site | x-ray diffraction | A, B | — | — |
| 3SAG | Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site | x-ray diffraction | A, B | — | — |
| 3SAH | Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site | x-ray diffraction | A, B | — | — |
| 3SAH | Crystal structure of the human RRP6 catalytic domain with Y436A mutation in the catalytic site | x-ray diffraction | A, B | — | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | J | — | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | J | — | — |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite MAP after focused reconstruction | electron microscopy | J | — | — |
| 7MQA | Cryo-EM structure of the human SSU processome, state post-A1 | electron microscopy | NV | — | — |
| Q01780 | AlphaFold monomer V2.0 prediction for exosome component 10 (Q01780) | predicted | A | — | — |
Experiment against prediction
- 3SAH chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.77 Å
- 3SAH chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.77 Å
- 3SAG chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.81 Å
- 3SAG chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.81 Å
- 3SAF chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.88 Å
- 3SAF chain B against the predicted model Q01780: TM-score 0.98, RMSD 0.88 Å
- 3SAF chain A against the predicted model Q01780: TM-score 0.98, RMSD 0.91 Å
- 3SAF chain A against the predicted model Q01780: TM-score 0.98, RMSD 0.91 Å
- 3SAG chain A against the predicted model Q01780: TM-score 0.97, RMSD 1.04 Å
- 3SAG chain A against the predicted model Q01780: TM-score 0.97, RMSD 1.04 Å
Elsewhere
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