Research workbench

structure of DECD to DEAD mutation of human UAP56

Analyse structure of DECD to DEAD mutation of human UAP56 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1XTK
Type: protein
Length: 382 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.4
Source: Homo sapiens
Molecule: Probable ATP-dependent RNA helicase p47
UniProt: Q13838
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · resolution 2.4 · 1 distinct chain · 40% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable ATP-dependent RNA helicase p47	protein	382	40% helix, 17% strand	Q13838

Ligands and binding sites

BME · Beta-mercaptoethanol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	641	0.68	0.77	54	empty

Compared structures

1XTK · Structure of decd to dead mutation of human UAP56 · the same entry in another collection · chain A against A, TM-score 1.00
Q13838 · AlphaFold monomer V2.0 prediction for spliceosome RNA helicase DDX39B (Q13838) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13838
Elsewhere: RCSB PDB 1XTK · PDBe 1XTK · UniProt Q13838

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