Research workbench
Toxin protein from Staphylococcus aureus
Analyse Toxin protein from Staphylococcus aureus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7EWI
- Type
- protein
- Length
- 446 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.93
- Source
- Staphylococcus aureus
- Molecule
- Endoribonuclease MazF
- UniProt
- L7PFJ6
- Ligands
- PO4
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · resolution 1.93 · 3 distinct chains · 19% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, D | Endoribonuclease MazF | protein | 111 | 20% helix, 34% strand | L7PFJ6 |
| B | Endoribonuclease MazF | protein | 109 | 20% helix, 35% strand | L7PFJ6 |
| A | Endoribonuclease MazF | protein | 115 | 17% helix, 33% strand | L7PFJ6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.55 | 0.78 | 30 | empty |
| 2 | 113 | 0.38 | 0.74 | 22 | empty |
| 3 | 63 | 0.34 | 0.77 | 13 | empty |
| 4 | 64 | 0.32 | 0.75 | 13 | GOL |
Interfaces
3 interfaces between chains.
- B–D · 1773 Ų buried · 35 hydrogen bonds · protein-protein
- C–A · 1765 Ų buried · 34 hydrogen bonds · protein-protein
- C–B · 309 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7EWI · Toxin protein from staphylococcus aureus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L7PFJ6
- Elsewhere: RCSB PDB 7EWI · PDBe 7EWI · UniProt L7PFJ6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.