MolNFT v1 · #177867 · protein
Toxin protein from staphylococcus aureus
7EWI · Endoribonuclease mazf: “Toxin protein from staphylococcus aureus”. X-ray diffraction, 1 ligand (PO4), 4 pockets (best druggability 0.55). MolNFT v1 #177867 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7EWI
- Type
- protein
- Length
- 446 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoribonuclease mazf
- UniProt
- L7PFJ6
- Ligands
- PO4
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 3 distinct chains · 19% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, D | Endoribonuclease mazf | protein | 111 | 20% helix, 34% strand | L7PFJ6 |
| B | Endoribonuclease mazf | protein | 109 | 20% helix, 35% strand | L7PFJ6 |
| A | Endoribonuclease mazf | protein | 115 | 17% helix, 33% strand | L7PFJ6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.55 | 0.78 | 30 | empty |
| 2 | 113 | 0.38 | 0.74 | 22 | empty |
| 3 | 63 | 0.34 | 0.77 | 13 | empty |
| 4 | 64 | 0.32 | 0.75 | 13 | GOL |
Interfaces
3 interfaces between chains.
- B–D · 1773 Ų buried · 35 hydrogen bonds · protein-protein
- C–A · 1765 Ų buried · 34 hydrogen bonds · protein-protein
- C–B · 309 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7EWI · Toxin protein from Staphylococcus aureus · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L7PFJ6
- Elsewhere: RCSB PDB 7EWI · PDBe 7EWI · UniProt L7PFJ6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.