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Crystal structure of EphA7 mutant G656E

Analyse Crystal structure of EphA7 mutant G656E in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7EEF
Type: protein
Length: 283 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.6
Source: Homo sapiens
Molecule: Ephrin type-A receptor 7
EC: 2.7.10.1
UniProt: Q15375
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · resolution 2.6 · 1 distinct chain · 41% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-A receptor 7 (EC 2.7.10.1)	protein	283	41% helix, 15% strand	Q15375

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	462	0.66	0.78	42	empty

Compared structures

7EEF · Crystal structure of EPHA7 mutant G656E · the same entry in another collection · chain A against A, TM-score 1.00
Q15375 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 7 (Q15375) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15375
Elsewhere: RCSB PDB 7EEF · PDBe 7EEF · UniProt Q15375

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