Research workbench
Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: substrate-free)
Analyse Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7CAQ
- Type
- protein
- Length
- 415 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.69
- Source
- Methanosarcina mazei Go1
- Molecule
- cis-prenyltransferase MM_0014
- Ligands
- PLM, PO4
- Pockets
- 5 · best druggability 0.81
Structure
x-ray diffraction · resolution 1.69 · 2 distinct chains · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | cis-prenyltransferase MM_0014 | protein | 215 | 42% helix, 17% strand | — |
| B | cis-prenyltransferase MM_0014 | protein | 200 | 40% helix, 17% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 172 | 0.81 | 0.96 | 36 | PLM, PO4 |
| 2 | 307 | 0.76 | 0.87 | 41 | PO4 |
| 3 | 75 | 0.32 | 0.75 | 17 | empty |
| 4 | 57 | 0.28 | 0.74 | 11 | empty |
| 5 | 51 | 0.27 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1466 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 7CAQ · Versatile cis-prenyltransferase MM_0014 from methanosarcina mazei (crystal type… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7CAQ · PDBe 7CAQ
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