Research workbench
bovine ATP synthase stator domain, state 1
Analyse bovine ATP synthase stator domain, state 1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ZIQ
- Type
- protein
- Length
- 1,385 residues
- Chains
- 15
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.33
- Source
- Bos taurus
- Molecule
- ATP synthase protein 8; ATP synthase subunit a; ATP synthase subunit d, mitochondrial…
- UniProt
- P03929, P00847, P13620, Q00361, Q28851, Q28852, P14790, Q3ZBI7, P32876, P13619, P02721, P13621, P19483
- Pockets
- 20 · best druggability 0.76
Structure
electron microscopy · resolution 4.33 · 15 distinct chains · 68% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 8 | ATP synthase protein 8 | protein | 41 | 66% helix, 0% strand | P03929 |
| a | ATP synthase subunit a | protein | 226 | 74% helix, 0% strand | P00847 |
| d | ATP synthase subunit d, mitochondrial | protein | 155 | 56% helix, 1% strand | P13620 |
| e | ATP synthase subunit e, mitochondrial | protein | 41 | 83% helix, 0% strand | Q00361 |
| f | ATP synthase subunit f, mitochondrial | protein | 83 | 57% helix, 2% strand | Q28851 |
| g | ATP synthase subunit g, mitochondrial | protein | 79 | 76% helix, 1% strand | Q28852 |
| j | ATP synthase subunit ATP5MPL, mitochondrial | protein | 48 | 81% helix, 0% strand | P14790 |
| k | ATP synthase membrane subunit DAPIT, mitochondrial | protein | 36 | 75% helix, 0% strand | Q3ZBI7 |
| M | ATP synthase F(0) complex subunit C1, mitochondrial | protein | 68 | 90% helix, 0% strand | P32876 |
| N | ATP synthase F(0) complex subunit C1, mitochondrial | protein | 75 | 91% helix, 0% strand | P32876 |
| O | ATP synthase F(0) complex subunit C1, mitochondrial | protein | 44 | 80% helix, 0% strand | P32876 |
| b | ATP synthase F(0) complex subunit B1, mitochondrial | protein | 209 | 83% helix, 2% strand | P13619 |
| h | ATP synthase-coupling factor 6, mitochondrial | protein | 62 | 56% helix, 0% strand | P02721 |
| S | ATP synthase subunit O, mitochondrial | protein | 129 | 50% helix, 19% strand | P13621 |
| C | ATP synthase subunit alpha, mitochondrial | protein | 89 | 12% helix, 42% strand | P19483 |
Pockets
20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 680 | 0.76 | 0.81 | 65 | empty |
| 2 | 786 | 0.76 | 0.79 | 65 | empty |
| 3 | 235 | 0.76 | 0.90 | 43 | empty |
| 4 | 413 | 0.73 | 0.83 | 45 | empty |
| 5 | 317 | 0.69 | 0.83 | 45 | empty |
Interfaces
32 interfaces between chains.
- d–b · 3134 Ų buried · 27 hydrogen bonds · protein-protein
- 8–a · 1506 Ų buried · 3 hydrogen bonds · protein-protein
- b–h · 1414 Ų buried · 18 hydrogen bonds · protein-protein
- M–N · 1395 Ų buried · 6 hydrogen bonds · protein-protein
- a–b · 1182 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 modified (methylation).
Compared structures
- 6ZIQ · Bovine ATP synthase stator domain, state 1 · the same entry in another collection · chain d against d, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03929
- Every structure of UniProt P00847
- Every structure of UniProt P13620
- Every structure of UniProt Q00361
- Every structure of UniProt Q28851
- Every structure of UniProt Q28852
- Every structure of UniProt P14790
- Every structure of UniProt Q3ZBI7
- Every structure of UniProt P32876
- Every structure of UniProt P13619
- Every structure of UniProt P02721
- Every structure of UniProt P13621
- Every structure of UniProt P19483
- Elsewhere: RCSB PDB 6ZIQ · PDBe 6ZIQ · UniProt P03929 · UniProt P00847 · UniProt P13620 · UniProt Q00361 · UniProt Q28851 · UniProt Q28852 · UniProt P14790 · UniProt Q3ZBI7 · UniProt P32876 · UniProt P13619 · UniProt P02721 · UniProt P13621 · UniProt P19483
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.