Research workbench
Structural characterization of the type III secretion system pilotin-secretin complex InvH-InvG by NMR spectroscopy
Analyse Structural characterization of the type III secretion system pilotin-secretin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6XFL
- Type
- protein
- Length
- 124 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- NOT
- Source
- Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
- Molecule
- Type 3 secretion system pilotin; Type 3 secretion system secretin
- UniProt
- P0CL43, P35672
- Pockets
- 3 · best druggability 0.43
Structure
solution nmr · resolution NOT · 2 distinct chains · 52% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type 3 secretion system pilotin | protein | 79 | 65% helix, 0% strand | P0CL43 |
| B | Type 3 secretion system secretin | protein | 45 | 31% helix, 0% strand | P35672 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.43 | 0.81 | 19 | empty |
| 2 | 93 | 0.41 | 0.77 | 18 | empty |
| 3 | 65 | 0.39 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 936 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6XFL · Structural characterization of the type III secretion system pilotin- secretin complex… · the same entry in another collection · chain A against A, TM-score 1.00
- P0CL43 · AlphaFold monomer V2.0 prediction for spi-1 type 3 secretion system pilotin (P0CL43) · a predicted model of the same protein · chain A against A, TM-score 0.68
- P35672 · AlphaFold monomer V2.0 prediction for spi-1 type 3 secretion system secretin (P35672) · a predicted model of the same protein · chain B against A, TM-score 0.42
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CL43
- Every structure of UniProt P35672
- Elsewhere: RCSB PDB 6XFL · PDBe 6XFL · UniProt P0CL43 · UniProt P35672
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