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A class C beta-lactamase mutant - Y150F

Analyse A class C beta-lactamase mutant - Y150F in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6M5H
Type: protein
Length: 361 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.2
Source: Klebsiella pneumoniae
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: Q9XB24
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · resolution 1.2 · 1 distinct chain · 40% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	361	40% helix, 24% strand	Q9XB24

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	340	0.62	0.78	44	empty
2	56	0.29	0.74	13	empty

Compared structures

6M5H · A class C beta-lactamase mutant - Y150F · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9XB24
Elsewhere: RCSB PDB 6M5H · PDBe 6M5H · UniProt Q9XB24

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