Research workbench
Tel1 kinase butterfly symmetric dimer
Analyse Tel1 kinase butterfly symmetric dimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6JXC
- Type
- protein
- Length
- 2,345 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.1
- Source
- Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
- Molecule
- Serine/threonine-protein kinase TEL1
- EC
- 2.7.11.1
- UniProt
- P38110
- Pockets
- 20 · best druggability 0.85
Structure
electron microscopy · resolution 4.1 · 1 distinct chain · 59% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine/threonine-protein kinase TEL1 (EC 2.7.11.1) | protein | 2345 | 59% helix, 0% strand | P38110 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1175 | 0.85 | 0.85 | 113 | empty |
| 2 | 941 | 0.84 | 0.86 | 103 | empty |
| 3 | 592 | 0.84 | 0.89 | 77 | empty |
| 4 | 404 | 0.78 | 0.87 | 70 | empty |
| 5 | 364 | 0.76 | 0.87 | 67 | empty |
Compared structures
- 6JXC · TEL1 kinase butterfly symmetric dimer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38110
- Elsewhere: RCSB PDB 6JXC · PDBe 6JXC · UniProt P38110
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