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Chimeric Rat C5a

Analyse Chimeric Rat C5a in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6JV7
Type: protein
Length: 154 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.309
Molecule: Chimeric-rC5a; D-anaphylatoxin C5a
UniProt: P08650
Ligands: SO4

Structure

x-ray diffraction · resolution 1.309 · 2 distinct chains · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chimeric-rC5a	protein	77	64% helix, 0% strand	P08650
B	D-anaphylatoxin C5a	protein	77	62% helix, 0% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 529 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 73 d-amino, 6 disulfide, 3 modified (D-amino acid, disulfide, nonstandard).

Compared structures

6JV7 · Chimeric rat C5A · the same entry in another collection · chain A against A, TM-score 1.00
P08650 · AlphaFold monomer V2.0 prediction for complement C5 (P08650) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08650
Elsewhere: RCSB PDB 6JV7 · PDBe 6JV7 · UniProt P08650

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