Crystal structure of a mini fungal lectin, PhoSL in complex with core-fucosylated chitobiose

Structure

x-ray diffraction · resolution 1.12 · 1 distinct chain · 0% helix, 65% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains B, A, C
• FUC · alpha-L-fucopyranose · sugar · 3 copies · chains A, B, C
• GOL · Glycerol · additive · 4 copies · chains A, C, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

3 interfaces between chains.

• A–B · 705 Ų buried · 17 hydrogen bonds · protein-protein
• B–C · 704 Ų buried · 21 hydrogen bonds · protein-protein
• A–C · 698 Ų buried · 22 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 6JK3 · Crystal structure of a mini fungal lectin, phosl in complex with core- fucosylated… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A3B6UEU4
• Elsewhere: RCSB PDB 6JK3 · PDBe 6JK3 · UniProt A0A3B6UEU4