Research workbench

Crystal Structure Analysis of a Eukaryotic Membrane Protein

Analyse Crystal Structure Analysis of a Eukaryotic Membrane Protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IZ5
Type: protein
Length: 224 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.701
Source: Xenopus laevis
Molecule: Trimeric intracellular cation channel type B-B
UniProt: Q6GN30
Pockets: 3 · best druggability 0.65

Structure

x-ray diffraction · resolution 3.701 · 1 distinct chain · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Trimeric intracellular cation channel type B-B	protein	224	77% helix, 0% strand	Q6GN30

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	383	0.65	0.79	43	empty
2	177	0.49	0.77	22	empty
3	51	0.35	0.78	11	empty

Compared structures

6IZ5 · Crystal structure analysis of a eukaryotic membrane protein · the same entry in another collection · chain A against A, TM-score 1.00
Q6GN30 · AlphaFold monomer V2.0 prediction for trimeric intracellular cation channel type B-B… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6GN30
Elsewhere: RCSB PDB 6IZ5 · PDBe 6IZ5 · UniProt Q6GN30

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.