MolNFT v1 · #152965 · protein
Crystal structure analysis of a eukaryotic membrane protein
6IZ5 · Trimeric intracellular cation channel type B-B: “Crystal structure analysis of a eukaryotic membrane protein”. X-ray diffraction, 3 pockets (best druggability 0.65). MolNFT v1 #152965 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6IZ5
- Type
- protein
- Length
- 224 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trimeric intracellular cation channel type B-B
- UniProt
- Q6GN30
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trimeric intracellular cation channel type B-B | protein | 224 | 77% helix, 0% strand | Q6GN30 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 383 | 0.65 | 0.79 | 43 | empty |
| 2 | 177 | 0.49 | 0.77 | 22 | empty |
| 3 | 51 | 0.35 | 0.78 | 11 | empty |
Compared structures
- 6IZ5 · Crystal Structure Analysis of a Eukaryotic Membrane Protein · the same entry in another collection · chain A against A, TM-score 1.00
- Q6GN30 · AlphaFold monomer V2.0 prediction for trimeric intracellular cation channel type B-B… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6GN30
- Elsewhere: RCSB PDB 6IZ5 · PDBe 6IZ5 · UniProt Q6GN30
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