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Blood group synthase AAGlyB in its apo form cryoprotected with PEG 3350

Analyse Blood group synthase AAGlyB in its apo form cryoprotected with PEG 3350 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6GWZ
Type: protein
Length: 288 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.65
Source: Homo sapiens
Molecule: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase…
UniProt: F0X360
Ligands: SO4
Pockets: 1 · best druggability 0.62

Structure

x-ray diffraction · resolution 1.65 · 1 distinct chain · 32% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase)	protein	288	32% helix, 19% strand	F0X360

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	414	0.62	0.77	32	empty

Compared structures

6GWZ · Blood group synthase aaglyb in its apo form cryoprotected with peg 3350 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F0X360
Elsewhere: RCSB PDB 6GWZ · PDBe 6GWZ · UniProt F0X360

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