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Structure of the soluble AhlB of the tripartite alpha-pore forming toxin, AHL, from Aeromonas hydrophila.
Analyse Structure of the soluble AhlB of the tripartite alpha-pore forming toxin, AHL… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6GRK
- Type
- protein
- Length
- 1,055 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.33
- Source
- Aeromonas hydrophila
- Molecule
- AhlB
- UniProt
- A0A081US78
- Pockets
- 15 · best druggability 0.72
Structure
x-ray diffraction · resolution 2.33 · 2 distinct chains · 77% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, I | AhlB | protein | 354 | 76% helix, 4% strand | A0A081US78 |
| B | AhlB | protein | 347 | 78% helix, 4% strand | A0A081US78 |
Pockets
15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 953 | 0.72 | 0.76 | 94 | empty |
| 2 | 67 | 0.61 | 0.91 | 18 | empty |
| 3 | 67 | 0.60 | 0.90 | 21 | empty |
| 4 | 61 | 0.58 | 0.90 | 19 | empty |
| 5 | 140 | 0.49 | 0.78 | 26 | empty |
Interfaces
3 interfaces between chains.
- A–B · 907 Ų buried · 2 hydrogen bonds · protein-protein
- A–I · 600 Ų buried · 9 hydrogen bonds · protein-protein
- I–B · 78 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 6GRK · Structure of the soluble ahlb of the tripartite alpha-pore forming toxin, ahl, from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A081US78
- Elsewhere: RCSB PDB 6GRK · PDBe 6GRK · UniProt A0A081US78
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