MolNFT v1 · #150371 · protein

Structure of the soluble ahlb of the tripartite alpha-pore forming toxin, ahl, from aeromonas hydrophila.

6GRK: “Structure of the soluble ahlb of the tripartite alpha-pore forming toxin, ahl, from aeromonas hydrophila.”. X-ray diffraction, 15 pockets (best druggability 0.72). MolNFT v1 #150371 on GenesisL1: 3D structure, binding sites and…

PDB: 6GRK
Type: protein
Length: 1,055 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ahlb
UniProt: A0A081US78
Pockets: 15 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, I	Ahlb	protein	354	76% helix, 4% strand	A0A081US78
B	Ahlb	protein	347	78% helix, 4% strand	A0A081US78

Pockets

15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	953	0.72	0.76	94	empty
2	67	0.61	0.91	18	empty
3	67	0.60	0.90	21	empty
4	61	0.58	0.90	19	empty
5	140	0.49	0.78	26	empty

Interfaces

3 interfaces between chains.

A–B · 907 Å² buried · 2 hydrogen bonds · protein-protein
A–I · 600 Å² buried · 9 hydrogen bonds · protein-protein
I–B · 78 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6GRK · Structure of the soluble AhlB of the tripartite alpha-pore forming toxin, AHL, from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A081US78
Elsewhere: RCSB PDB 6GRK · PDBe 6GRK · UniProt A0A081US78

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