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C-terminal domain of the 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA.

Analyse C-terminal domain of the 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5EOV
Type: protein
Length: 205 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.701
Source: Mycobacterium tuberculosis
Molecule: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
EC: 2.1.1.226, 2.1.1.227
UniProt: P9WJ62
Pockets: 2 · best druggability 0.32

Structure

x-ray diffraction · resolution 1.701 · 1 distinct chain · 37% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA (EC 2.1.1.226, 2.1.1.227)	protein	205	37% helix, 23% strand	P9WJ62

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.32	0.76	17	empty
2	60	0.26	0.72	20	empty

Compared structures

5EOV · C-terminal domain of the 16S/23S rRNA (cytidine-2'-O)- methyltransferase tlya. · the same entry in another collection · chain A against A, TM-score 1.00
P9WJ62 · AlphaFold monomer V2.0 prediction for 16S/23S rRNA (cytidine-2'-O)-methyltransferase tlya… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P9WJ62
Elsewhere: RCSB PDB 5EOV · PDBe 5EOV · UniProt P9WJ62

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