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Reaction of phosphorylated CheY with imidazole 3 of 3

Analyse Reaction of phosphorylated CheY with imidazole 3 of 3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5DKF
Type: protein
Length: 256 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.94
Source: Escherichia coli O157:H7
Molecule: Chemotaxis protein CheY
UniProt: P0AE68
Ligands: BEF, MN
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · resolution 1.94 · 1 distinct chain · 45% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Chemotaxis protein CheY	protein	128	45% helix, 16% strand	P0AE68

Ligands and binding sites

BEF · Beryllium trifluoride ion · ligand · 2 copies · chains A, B
MN · Manganese (II) ion · metal · 2 copies · chains A, B
IMD · Imidazole · additive · 5 copies · chains A, B
GOL · Glycerol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	254	0.56	0.77	44	empty

Interfaces

1 interface between chains.

A–B · 608 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

5DKF · Reaction of phosphorylated chey with imidazole 3 of 3 · the same entry in another collection · chain A against A, TM-score 1.00
P0AE68 · AlphaFold monomer V2.0 prediction for chemotaxis protein chey (P0AE68) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AE68
Elsewhere: RCSB PDB 5DKF · PDBe 5DKF · UniProt P0AE68

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