Research workbench
Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A
Analyse Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5DJO
- Type
- protein
- Length
- 318 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.74
- Source
- Mus musculus
- Molecule
- Kinesin-like protein
- UniProt
- F8VQ75
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · resolution 1.74 · 2 distinct chains · 27% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Kinesin-like protein | protein | 158 | 27% helix, 31% strand | F8VQ75 |
| B | Kinesin-like protein | protein | 160 | 26% helix, 32% strand | F8VQ75 |
Ligands and binding sites
- FMT · Formic acid · additive · 5 copies · chains A, B
- ACY · Acetic acid · additive · chains B
- PEG · Di(hydroxyethyl)ether · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 134 | 0.58 | 0.84 | 26 | empty |
| 2 | 76 | 0.32 | 0.74 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 2228 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 5DJO · Crystal structure of the CC1-fha tandem of kinesin-3 KIF13A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F8VQ75
- Elsewhere: RCSB PDB 5DJO · PDBe 5DJO · UniProt F8VQ75
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