Research workbench
X-ray structure of the CCL2 lectin in complex with sialyl lewis X
Analyse X-ray structure of the CCL2 lectin in complex with sialyl lewis X in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4USO
- Type
- protein
- Length
- 531 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.95
- Source
- COPRINOPSIS CINEREA
- Molecule
- CCL2 lectin
- UniProt
- B3GA02
- Ligands
- NAG, GAL, SIA, FUC
Structure
x-ray diffraction · resolution 1.95 · 4 distinct chains · 3% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CCL2 lectin | protein | 136 | 4% helix, 47% strand | B3GA02 |
| B | CCL2 lectin | protein | 135 | 2% helix, 47% strand | B3GA02 |
| C | CCL2 lectin | protein | 130 | 2% helix, 47% strand | B3GA02 |
| D | CCL2 lectin | protein | 130 | 5% helix, 47% strand | B3GA02 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- GAL · beta-D-galactopyranose · sugar · chains A
- SIA · N-acetyl-alpha-neuraminic acid · sugar · chains A
- FUC · alpha-L-fucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
2 interfaces between chains.
- C–D · 693 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 688 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 4USO · X-ray structure of the CCL2 lectin in complex with sialyl lewis X · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B3GA02
- Elsewhere: RCSB PDB 4USO · PDBe 4USO · UniProt B3GA02
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