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Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with L-tartrate (orthorhombic crystal form)

Analyse Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4PMQ
Type: protein
Length: 204 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.61
Source: Mycobacterium tuberculosis
Molecule: Tat-secreted protein Rv2525c
UniProt: P95028
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · resolution 1.61 · 1 distinct chain · 35% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tat-secreted protein Rv2525c	protein	204	35% helix, 23% strand	P95028

Ligands and binding sites

TLA · L(+)-tartaric acid · additive · 3 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	142	0.49	0.78	24	TLA, GOL

Compared structures

4PMQ · Crystal structure of the mycobacterium tuberculosis tat-secreted protein RV2525C in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P95028
Elsewhere: RCSB PDB 4PMQ · PDBe 4PMQ · UniProt P95028

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