Research workbench
Crystal structure of cisplatin bound to a plasmodium falciparum glutaredoxin 1 (PfGrx1)
Analyse Crystal structure of cisplatin bound to a plasmodium falciparum glutaredoxin 1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4N0Z
- Type
- protein
- Length
- 107 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.7
- Source
- Plasmodium falciparum
- Molecule
- Glutaredoxin
- EC
- 1.20.4.1
- UniProt
- Q9NLB2
- Ligands
- CPT
Structure
x-ray diffraction · resolution 1.7 · 1 distinct chain · 53% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutaredoxin (EC 1.20.4.1) | protein | 107 | 53% helix, 17% strand | Q9NLB2 |
Ligands and binding sites
- CPT · Cisplatin · ligand · chains A
- MPO · 3[N-morpholino]propane sulfonic acid · additive · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4N0Z · Crystal structure of cisplatin bound to a plasmodium falciparum glutaredoxin 1 (PFGRX1) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NLB2
- Elsewhere: RCSB PDB 4N0Z · PDBe 4N0Z · UniProt Q9NLB2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.