GL1X · GenesisL1 explorer

Ligand · MPO

MPO · 3[N-morpholino]propane sulfonic acid

MPO, 3[N-morpholino]propane sulfonic acid (C7 H15 N O4 S, 209.3 g/mol), in the MolNFT structures on GenesisL1: bound in 95 records (66 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
MPO
Formula
C7 H15 N O4 S
Class
additive
Structures
95
PDB entries
66

Binding sites

MPO in 95 structures; the first of them:

  • 4XP9 · X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine · MPO C704 · binds GLU222, TRP237
  • 4Z6Z · Structure of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-sulfonyl… · MPO A404 · binds ILE283, THR284, TRP285, ASP289, PHE341, THR342, ARG343, ALA344 and 1 more
  • 5BSF · Crystal structure of Medicago truncatula (delta)1-Pyrroline-5-Carboxylate Reductase… · MPO A302 · binds LYS80, PRO81, GLN82, ALA106, MET126, THR176, GLY180, SER181 and 3 more
  • 5CSQ · The structure of the NK1 fragment of HGF/SF complexed with MOPS · MPO A301 · binds HIS160, PHE162, ARG181, GLU183, TRP188, PHE190, ARG197, TYR198
  • 5KGP · X-ray structure of a glucosamine N-Acetyltransferase from Clostridium acetobutylicum in… · MPO B403 · binds GLN40, TRP62, SER66, LEU69, TYR77, SER116, ASP117, THR118 and 2 more
  • 5VA8 · Crystal Structure of Short-chain dehydrogenase/reductase SDR from Burkholderia phymatum… · MPO A303 · binds PRO93, PRO94, ASN99, THR101, ASP103, ASP104, ARG107
  • 5WB9 · Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E… · MPO G510 · binds ARG327, ILE420, LYS421, GLN422, ILE423
  • 5Z3M · Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from… · MPO A201 · binds CYS12, THR13, GLY14, ASN15, LEU16, CYS17, ARG18, LEU45 and 4 more
  • 6CBO · X-ray structure of GenB1 from micromonospora echinospora in complex with neamine and PLP… · MPO A501 · binds GLY8, LEU11, ALA12, GLN13, GLU14, PRO15, ARG19, PRO25 and 1 more
  • 6ET2 · Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) · MPO A900 · binds SER85, PRO87, GLU128, ALA129, ILE159, LEU162, PHE173, ALA207 and 9 more
  • 6FBQ · Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human… · MPO A303 · binds ALA136, LYS145, GLY148, VAL149, TYR150, MET198
  • 6H1T · Structure of the BM3 heme domain in complex with clotrimazole · MPO B504 · binds ILE366, TRP367, ARG375, ARG378, ALA384, ILE385, PRO386
  • 6HL3 · wild-type NuoEF from Aquifex aeolicus - oxidized form bound to NAD+ · MPO B506 · binds TYR34, ASP37, GLY38, GLY39, LEU113, GLU116, PHE229, SER232 and 1 more
  • 6HLA · wild-type NuoEF from Aquifex aeolicus - reduced form bound to NADH · MPO B505 · binds TYR34, ASP37, GLY38, GLY39, LEU113, GLU116, PRO228, PHE229 and 1 more

Residues it binds most

THR 74, ALA 68, GLY 103, ASP 96, PRO 90, SER 79, ARG 74, LYS 50, GLU 64, PHE 57 (residue and the binding sites it lines).

Found with

  • MPD · (4S)-2-methyl-2,4-pentanediol
  • EDO · 1,2-ethanediol
  • CL · Chloride ion
  • GOL · Glycerol
  • NA · Sodium ion
  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • PGE · Triethylene glycol
  • FES · Fe2/s2 (inorganic) cluster
  • FMN · Flavin mononucleotide
  • SF4 · Iron/sulfur cluster
  • PEG · Di(hydroxyethyl)ether

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.