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MazF from S. aureus crystal form II, C2221, 2.3 A

Analyse MazF from S. aureus crystal form II, C2221, 2.3 A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4MZT
Type: protein
Length: 227 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.303
Source: Staphylococcus aureus subsp. aureus
Molecule: MazF mRNA interferase
EC: 3.1.-.-
UniProt: Q7A4G9
Pockets: 1 · best druggability 0.26

Structure

x-ray diffraction · resolution 2.303 · 2 distinct chains · 20% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MazF mRNA interferase (EC 3.1.-.-)	protein	114	20% helix, 38% strand	Q7A4G9
B	MazF mRNA interferase (EC 3.1.-.-)	protein	113	20% helix, 38% strand	Q7A4G9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.26	0.74	15	empty

Interfaces

1 interface between chains.

A–B · 1294 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

4MZT · Mazf from S. aureus crystal form II, C2221, 2.3 a · the same entry in another collection · chain A against A, TM-score 1.00
Q7A4G9 · AlphaFold monomer V2.0 prediction for endoribonuclease mazf (Q7A4G9) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7A4G9
Elsewhere: RCSB PDB 4MZT · PDBe 4MZT · UniProt Q7A4G9

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