UniProt Q7A4G9
Endoribonuclease MazF (Q7A4G9)
Endoribonuclease MazF (UniProt Q7A4G9), EC 3.1.-.-: 15 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7A4G9
- Protein
- Endoribonuclease MazF
- EC
- 3.1.-.-
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 25 · 5 records with a druggable one
Structures
16 records of Q7A4G9 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MZM | MazF from S. aureus crystal form I, P212121, 2.1 A | x-ray diffraction | A, B, C, D | — | — |
| 4MZM | Mazf from S. aureus crystal form I, P212121, 2.1 a | x-ray diffraction | A, B, C, D | — | — |
| 4MZP | MazF from S. aureus crystal form III, C2221, 2.7 A | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4MZP | Mazf from S. aureus crystal form III, C2221, 2.7 a | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4MZT | MazF from S. aureus crystal form II, C2221, 2.3 A | x-ray diffraction | A, B | — | — |
| 4MZT | Mazf from S. aureus crystal form II, C2221, 2.3 a | x-ray diffraction | A, B | — | — |
| 5DLO | S. aureus MazF in complex with substrate analogue | x-ray diffraction | A | CL | — |
| 9G1Y | Staphycoccus aureus MazF in complex with Nabobody 3 | x-ray diffraction | A, B | — | 4 (best 0.60) |
| 9G2A | Staphylococcus aureus MazF in complex with nanobody 4 | x-ray diffraction | A, B | — | 2 (best 0.52) |
| 9G2G | Staphylococcus aureus MazF in complex with nanobody 5 | x-ray diffraction | A, B | — | 2 (best 0.60) |
| 9G48 | Staphylococcus aureus MazF in complex with Nanobody 6 | x-ray diffraction | A, B | CD | 3 (best 0.72) |
| 9G4G | Staphylococcus aureus MazF in complex with Nanobody 9 | x-ray diffraction | A | — | 1 (best 0.49) |
| 9G5L | Stapylococcus aureus MazF in complex with nanobody 10 | x-ray diffraction | A | CL | 1 (best 0.35) |
| 9G5Z | Nanobody-mediated activation and inhibition of Staphylococcus aureus MazF | x-ray diffraction | A, B | CL | 3 (best 0.49) |
| 9G7K | Staphylococcus aureus MazF in complex with Nanobody 12 | x-ray diffraction | A, B, E, F | CL, SO4 | 9 (best 0.78) |
| Q7A4G9 | AlphaFold monomer V2.0 prediction for endoribonuclease mazf (Q7A4G9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4MZM chain B against the predicted model Q7A4G9: TM-score 0.98, RMSD 0.51 Å
- 4MZM chain B against the predicted model Q7A4G9: TM-score 0.98, RMSD 0.51 Å
- 4MZP chain C against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.74 Å
- 4MZP chain C against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.74 Å
- 4MZP chain A against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.77 Å
- 4MZP chain A against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.77 Å
- 4MZM chain C against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.57 Å
- 4MZM chain C against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.57 Å
- 5DLO chain A against the predicted model Q7A4G9: TM-score 0.97, RMSD 0.92 Å
- 4MZM chain A against the predicted model Q7A4G9: TM-score 0.96, RMSD 0.78 Å
Elsewhere
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