Research workbench
AlphaFold monomer V2.0 prediction for putative methyltransferase C9ORF114 (Q5T280)
Analyse AlphaFold monomer V2.0 prediction for putative methyltransferase C9ORF114… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5T280
- Type
- protein
- Length
- 376 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC7cc4fC1fc1b08Ba48e6eA6ee8b27b213776B21D
- Molecule
- Putative methyltransferase C9ORF114
- UniProt
- Q5T280
- Pockets
- 4 · best druggability 0.66
Structure
1 distinct chain · 40% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative methyltransferase C9ORF114 | protein | 376 | 40% helix, 16% strand | Q5T280 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.66 | 0.84 | 32 | empty |
| 2 | 218 | 0.49 | 0.75 | 24 | empty |
| 3 | 154 | 0.47 | 0.77 | 24 | empty |
| 4 | 55 | 0.26 | 0.73 | 14 | empty |
Compared structures
- 8QSU · Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome… · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 8QSW · Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome… · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 4RG1 · Methyltransferase domain of C9orf114 · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 4RG1 · Methyltransferase domain of C9ORF114 · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 8QSV · Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome… · an experimental structure of the same protein · chain A against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5T280
- Elsewhere: UniProt Q5T280 · AlphaFold DB Q5T280
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