Research workbench
AlphaFold monomer V2.0 prediction for zinc transporter 7 (Q8NEW0)
Analyse AlphaFold monomer V2.0 prediction for zinc transporter 7 (Q8NEW0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8NEW0
- Type
- protein
- Length
- 376 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x738c1929c69B751bD0Be0B962D9bac20B631aAc6
- Molecule
- Zinc transporter 7
- UniProt
- Q8NEW0
- Pockets
- 4 · best druggability 0.81
Structure
1 distinct chain · 55% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc transporter 7 | protein | 376 | 55% helix, 9% strand | Q8NEW0 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.81 | 0.94 | 35 | empty |
| 2 | 212 | 0.48 | 0.75 | 19 | empty |
| 3 | 91 | 0.47 | 0.81 | 24 | empty |
| 4 | 92 | 0.42 | 0.79 | 18 | empty |
Compared structures
- 8J80 · Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous… · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 8J7V · Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous… · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 8J7X · Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in… · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 8J7T · Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in… · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 8J7W · Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous… · an experimental structure of the same protein · chain A against A, TM-score 0.72
- 8J7U · Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing… · an experimental structure of the same protein · chain A against B, TM-score 0.71
- 8J7Y · Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in… · an experimental structure of the same protein · chain A against B, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NEW0
- Elsewhere: UniProt Q8NEW0 · AlphaFold DB Q8NEW0
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