UniProt Q8NEW0
Zinc transporter 7 (Q8NEW0)
Zinc transporter 7 (UniProt Q8NEW0): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NEW0
- Protein
- Zinc transporter 7
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 80 · 8 records with a druggable one
Structures
8 records of Q8NEW0 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J7T | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing… | electron microscopy | A, B | — | 6 (best 0.82) |
| 8J7U | Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing… | electron microscopy | A, B | ZN | 12 (best 0.82) |
| 8J7V | Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous… | electron microscopy | A, B | — | 10 (best 0.78) |
| 8J7W | Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations… | electron microscopy | A, B | ZN | 13 (best 0.78) |
| 8J7X | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in… | electron microscopy | A, B | — | 11 (best 0.87) |
| 8J7Y | Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in… | electron microscopy | A, B | ZN | 14 (best 0.86) |
| 8J80 | Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations… | electron microscopy | A, B | ZN | 10 (best 0.82) |
| Q8NEW0 | AlphaFold monomer V2.0 prediction for zinc transporter 7 (Q8NEW0) | predicted | A | — | 4 (best 0.81) |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 8J7W chain A against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.76 Å
- 8J7V chain A against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.82 Å
- 8J7U chain A against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.79 Å
- 8J7T chain A against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.83 Å
- 8J7X chain A against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.76 Å
- 8J7X chain B against the predicted model Q8NEW0: TM-score 0.94, RMSD 1.76 Å
- 8J80 chain A against the predicted model Q8NEW0: TM-score 0.93, RMSD 1.83 Å
- 8J7Y chain B against the predicted model Q8NEW0: TM-score 0.93, RMSD 1.85 Å
- 8J7Y chain A against the predicted model Q8NEW0: TM-score 0.93, RMSD 1.85 Å
- 8J7U chain B against the predicted model Q8NEW0: TM-score 0.92, RMSD 1.95 Å
Elsewhere
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