Research workbench
AlphaFold monomer V2.0 prediction for xylose isomerase (P12070)
Analyse AlphaFold monomer V2.0 prediction for xylose isomerase (P12070) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P12070
- Type
- protein
- Length
- 395 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd27f4D98eE625C1f8E81f7ac0eF38f876f24543e
- Molecule
- Xylose isomerase
- UniProt
- P12070
- Pockets
- 5 · best druggability 0.75
Structure
1 distinct chain · 49% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Xylose isomerase | protein | 395 | 49% helix, 10% strand | P12070 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.75 | 0.98 | 24 | empty |
| 2 | 402 | 0.62 | 0.77 | 40 | empty |
| 3 | 206 | 0.48 | 0.74 | 22 | empty |
| 4 | 99 | 0.40 | 0.77 | 14 | empty |
| 5 | 80 | 0.33 | 0.74 | 21 | empty |
Compared structures
- 1XLM · D254E, D256E mutant of D-xylose isomerase complexed with AL3 and xylitol · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLM · D254E, D256E mutant of D-xylose isomerase complexed with AL3 and xylitol · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLB · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLB · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLC · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLC · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLG · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLG · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4XIA · Structures of D-xylose isomerase from arthrobacter strain B3728 containing the inhibitors… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4XIA · Structures of D-xylose isomerase from arthrobacter strain B3728 containing the inhibitors… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLK · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1XLK · Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening… · an experimental structure of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P12070
- Elsewhere: UniProt P12070 · AlphaFold DB P12070
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