UniProt P12070
Xylose isomerase (P12070)
Xylose isomerase (UniProt P12070): 33 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12070
- Protein
- Xylose isomerase
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
34 records of P12070 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DID | Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by… | x-ray diffraction | A, B | — | — |
| 1DID | Observations of reaction intermediates and the mechanism of aldose- ketose interconversion by… | x-ray diffraction | A, B | — | — |
| 1DIE | Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by… | x-ray diffraction | A, B | — | — |
| 1DIE | Observations of reaction intermediates and the mechanism of aldose- ketose interconversion by… | x-ray diffraction | A, B | — | — |
| 1XLA | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLA | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLB | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLB | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLC | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLC | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLD | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLD | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLE | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLE | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLF | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLF | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLG | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLG | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLH | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLH | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLI | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLI | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLJ | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLJ | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLK | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLK | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLL | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLL | Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed… | x-ray diffraction | A, B | — | — |
| 1XLM | D254E, D256E mutant of D-xylose isomerase complexed with AL3 and xylitol | x-ray diffraction | A, B | — | — |
| 1XLM | D254E, D256E mutant of D-xylose isomerase complexed with AL3 and xylitol | x-ray diffraction | A, B | — | — |
| 4XIA | Structures of D-xylose isomerase from arthrobacter strain B3728 containing the inhibitors xylitol… | x-ray diffraction | A, B | — | — |
| 4XIA | Structures of D-xylose isomerase from arthrobacter strain B3728 containing the inhibitors xylitol… | x-ray diffraction | A, B | — | — |
| 5XIA | Structures of D-xylose isomerase from arthrobacter strain B3728 containing the inhibitors xylitol… | x-ray diffraction | A, B | XYL, MG | — |
| P12070 | AlphaFold monomer V2.0 prediction for xylose isomerase (P12070) | predicted | A | — | 5 (best 0.75) |
Ligands
Experiment against prediction
- 1XLM chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLM chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLB chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLB chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLC chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLC chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLG chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 1XLG chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 4XIA chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
- 4XIA chain A against the predicted model P12070: TM-score 1.00, RMSD 0.25 Å
Elsewhere
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