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AlphaFold monomer V2.0 prediction for protein wnt-7A (O00755)

Analyse AlphaFold monomer V2.0 prediction for protein wnt-7A (O00755) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: O00755
Type: protein
Length: 349 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x622F878f08B9e89BA564bc58b0244ad72d265aaf
Molecule: Protein wnt-7A
UniProt: O00755
Pockets: 3 · best druggability 0.43

Structure

1 distinct chain · 42% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein wnt-7A	protein	349	42% helix, 22% strand	O00755

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	147	0.43	0.75	21	empty
2	61	0.31	0.76	19	empty
3	58	0.27	0.73	12	empty

Modifications

Observed in the structure: 11 disulfide (disulfide).

Compared structures

8TZO · Structure of human Wnt7a bound to WLS and CALR · an experimental structure of the same protein · chain A against A, TM-score 0.74
8TZP · Structure of human Wnt7a bound to WLS and RECK · an experimental structure of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00755
Elsewhere: UniProt O00755 · AlphaFold DB O00755

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