GL1X · GenesisL1 explorer

UniProt O00755

Protein Wnt-7a (O00755)

Protein Wnt-7a (UniProt O00755): 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
O00755
Protein
Protein Wnt-7a
Experimental structures
4
Predicted models
1
Ligands
4
Pockets
17 · 2 records with a druggable one

Structures

5 records of O00755 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4UZQStructure of the wnt deacylase notum in complex with O-palmitoleoyl serine - crystal form IX - 1.5Ax-ray diffractionB——
4UZQStructure of the wnt deacylase notum in complex with O-palmitoleoyl serine - crystal form IX - 1.5Ax-ray diffractionB——
8TZOStructure of human Wnt7a bound to WLS and CALRelectron microscopyANAG, GLC, PAM, POV6 (best 0.83)
8TZPStructure of human Wnt7a bound to WLS and RECKelectron microscopyAPAM, POV8 (best 0.83)
O00755AlphaFold monomer V2.0 prediction for protein wnt-7A (O00755)predictedA—3 (best 0.43)

Ligands

  • PAM · Palmitoleic acid · in 2 records
  • POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 2 records
  • GLC · alpha-D-glucopyranose · in 1 record
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record

Experiment against prediction

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.