Research workbench
AlphaFold monomer V2.0 prediction for WEE1-like protein kinase 2 (P0C1S8)
Analyse AlphaFold monomer V2.0 prediction for WEE1-like protein kinase 2 (P0C1S8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P0C1S8
- Type
- protein
- Length
- 567 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x57764D56d6101A81058fB5c5E4A885853213A02B
- Molecule
- WEE1-like protein kinase 2
- UniProt
- P0C1S8
- Pockets
- 6 · best druggability 0.69
Structure
1 distinct chain · 27% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | WEE1-like protein kinase 2 | protein | 567 | 27% helix, 10% strand | P0C1S8 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 831 | 0.69 | 0.75 | 70 | empty |
| 2 | 239 | 0.65 | 0.83 | 27 | empty |
| 3 | 287 | 0.51 | 0.74 | 33 | empty |
| 4 | 61 | 0.51 | 0.86 | 19 | empty |
| 5 | 66 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 5VDK · Crystal structure of human WEE2 kinase domain in complex with MK1775 · an experimental structure of the same protein · chain A against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C1S8
- Elsewhere: UniProt P0C1S8 · AlphaFold DB P0C1S8
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