UniProt P0C1S8
Wee1-like protein kinase 2 (P0C1S8)
Wee1-like protein kinase 2 (UniProt P0C1S8), EC 2.7.10.2: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0C1S8
- Protein
- Wee1-like protein kinase 2
- EC
- 2.7.10.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
3 records of P0C1S8 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VDK | Crystal structure of human WEE2 kinase domain in complex with MK1775 | x-ray diffraction | A | 8X7, PO4 | 1 (best 0.67) |
| 5VDK | Crystal structure of human WEE2 kinase domain in complex with MK1775 | x-ray diffraction | A | 8X7, PO4 | — |
| P0C1S8 | AlphaFold monomer V2.0 prediction for WEE1-like protein kinase 2 (P0C1S8) | predicted | A | — | 6 (best 0.69) |
Ligands
Experiment against prediction
- 5VDK chain A against the predicted model P0C1S8: TM-score 0.98, RMSD 0.92 Å
- 5VDK chain A against the predicted model P0C1S8: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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