Research workbench
AlphaFold monomer V2.0 prediction for pre-mRNA 3' end processing protein WDR33 (Q9C0J8)
Analyse AlphaFold monomer V2.0 prediction for pre-mRNA 3' end processing protein WDR33… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9C0J8
- Type
- protein
- Length
- 1,336 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3d4E27cf9065B918518565E961f228A07fD3933F
- Molecule
- Pre-mRNA 3' end processing protein WDR33
- UniProt
- Q9C0J8
- Pockets
- 4 · best druggability 0.76
Structure
1 distinct chain · 7% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA 3' end processing protein WDR33 | protein | 1336 | 7% helix, 12% strand | Q9C0J8 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 531 | 0.76 | 0.83 | 41 | empty |
| 2 | 118 | 0.66 | 0.89 | 20 | empty |
| 3 | 124 | 0.43 | 0.76 | 21 | empty |
| 4 | 71 | 0.42 | 0.81 | 14 | empty |
Compared structures
- 6URO · Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6URO · Cryo-EM structure of human CPSF160-WDR33-CPSF30-pas RNA-CSTF77 complex · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 8E3I · CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6DNH · Cryo-EM structure of human cpsf-160-WDR33-cpsf-30-pas RNA complex at 3.4 a resolution · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6DNH · Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 8R8R · Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6FUW · Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif… · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6FUW · Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif… · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6FBS · Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the pas aauaaa motif… · an experimental structure of the same protein · chain A against B, TM-score 0.28
- 6URG · Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 pim complex · an experimental structure of the same protein · chain A against B, TM-score 0.27
- 6URG · Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex · an experimental structure of the same protein · chain A against B, TM-score 0.27
- 8E3Q · CRYO-EM STRUCTURE OF the human MPSF · an experimental structure of the same protein · chain A against B, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9C0J8
- Elsewhere: UniProt Q9C0J8 · AlphaFold DB Q9C0J8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.