AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 12 (Q12220)

Structure

1 distinct chain · 23% helix, 41% strand (DSSP).

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Compared structures

• 6LQT · Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQS · Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQR · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQV · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 7D63 · Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQQ · Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQP · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 7D5S · Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6LQU · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 6KE6 · 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 7D5T · Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) · an experimental structure of the same protein · chain A against B2, TM-score 0.69
• 7D4I · Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA… · an experimental structure of the same protein · chain A against B2, TM-score 0.69

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q12220
• Elsewhere: UniProt Q12220 · AlphaFold DB Q12220