UniProt Q12220
U3 small nucleolar RNA-associated protein 12 (Q12220)
U3 small nucleolar RNA-associated protein 12 (UniProt Q12220): 13 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12220
- Protein
- U3 small nucleolar RNA-associated protein 12
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 13 · 4 records with a druggable one
Structures
14 records of Q12220 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WLC | The complete structure of the small subunit processome | electron microscopy | LQ | — | — |
| 5WYK | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | electron microscopy | BB | — | — |
| 6LQP | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) | electron microscopy | B2 | — | — |
| 6LQQ | Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) | electron microscopy | B2 | — | — |
| 6LQR | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) | electron microscopy | B2 | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | B2 | — | — |
| 6LQT | Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) | electron microscopy | B2 | — | — |
| 6LQU | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) | electron microscopy | B2 | — | — |
| 6LQV | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) | electron microscopy | B2 | — | — |
| 6ZQC | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 | electron microscopy | UL | — | 1 (best 0.86) |
| 6ZQE | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | electron microscopy | UL | — | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | UL | — | 1 (best 0.85) |
| 7D5T | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | electron microscopy | B2 | — | 2 (best 0.85) |
| Q12220 | AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 12 (Q12220) | predicted | A | — | 9 (best 0.79) |
Experiment against prediction
- 6ZQE chain UL against the predicted model Q12220: TM-score 0.79, RMSD 2.40 Å
- 6LQS chain B2 against the predicted model Q12220: TM-score 0.79, RMSD 2.23 Å
- 6LQT chain B2 against the predicted model Q12220: TM-score 0.79, RMSD 2.23 Å
- 6LQR chain B2 against the predicted model Q12220: TM-score 0.79, RMSD 2.26 Å
- 6LQV chain B2 against the predicted model Q12220: TM-score 0.79, RMSD 2.26 Å
- 7D5T chain B2 against the predicted model Q12220: TM-score 0.78, RMSD 2.34 Å
- 7AJT chain UL against the predicted model Q12220: TM-score 0.77, RMSD 2.20 Å
- 6ZQC chain UL against the predicted model Q12220: TM-score 0.77, RMSD 2.20 Å
- 6LQP chain B2 against the predicted model Q12220: TM-score 0.76, RMSD 2.26 Å
- 6LQQ chain B2 against the predicted model Q12220: TM-score 0.76, RMSD 2.26 Å
Elsewhere
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