Research workbench
AlphaFold monomer V2.0 prediction for sterol uptake control protein 2 (Q12151)
Analyse AlphaFold monomer V2.0 prediction for sterol uptake control protein 2 (Q12151) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q12151
- Type
- protein
- Length
- 913 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- Sterol uptake control protein 2
- UniProt
- Q12151
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 35% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol uptake control protein 2 | protein | 913 | 35% helix, 3% strand | Q12151 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 788 | 0.80 | 0.83 | 75 | empty |
| 2 | 112 | 0.76 | 0.95 | 23 | empty |
| 3 | 201 | 0.60 | 0.81 | 22 | empty |
| 4 | 106 | 0.56 | 0.84 | 18 | empty |
| 5 | 130 | 0.41 | 0.75 | 24 | empty |
Compared structures
- 4N9N · Crystal Structure of Saccharomyces cerevisiae Upc2 Transcription Factor fused with T4… · an experimental structure of the same protein · chain A against A, TM-score 0.28
- 4N9N · Crystal structure of saccharomyces cerevisiae UPC2 transcription factor fused with T4… · an experimental structure of the same protein · chain A against A, TM-score 0.28
- 7XB5 · Structure of the ligand-binding domain of S. cerevisiae Upc2 in fusion with T4 lysozyme · an experimental structure of the same protein · chain A against A, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12151
- Elsewhere: UniProt Q12151 · AlphaFold DB Q12151
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