Research workbench
AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 46 (P62068)
Analyse AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 46… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P62068
- Type
- protein
- Length
- 366 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf4ED13986579E8e227b3ED6c02276c648754EC27
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 46
- UniProt
- P62068
- Pockets
- 3 · best druggability 0.45
Structure
1 distinct chain · 31% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 46 | protein | 366 | 31% helix, 33% strand | P62068 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.45 | 0.81 | 17 | empty |
| 2 | 76 | 0.39 | 0.79 | 15 | empty |
| 3 | 54 | 0.30 | 0.76 | 17 | empty |
Compared structures
- 5CVO · WDR48:USP46~UBIQUITIN ternary complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 5CVO · WDR48:USP46~ubiquitin ternary complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 5CVN · WDR48 (2-580):USP46~ubiquitin ternary complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 5CVN · WDR48 (2-580):USP46~UBIQUITIN ternary complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 5L8H · Structure of USP46-UbVME · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 5L8H · Structure of USP46-ubvme · an experimental structure of the same protein · chain A against A, TM-score 0.84
- 5CVM · USP46~UBIQUITIN bea covalent complex · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 5CVM · USP46~ubiquitin BEA covalent complex · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 6JLQ · Crystal structure of human USP46-WDR48-WDR20 complex · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 6JLQ · Crystal structure of human USP46-WDR48-WDR20 complex · an experimental structure of the same protein · chain A against A, TM-score 0.75
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62068
- Elsewhere: UniProt P62068 · AlphaFold DB P62068
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