Research workbench
AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (Q8U094)
Analyse AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (Q8U094) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8U094
- Type
- protein
- Length
- 248 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- Tryptophan synthase alpha chain
- UniProt
- Q8U094
- Pockets
- 2 · best druggability 0.67
Structure
1 distinct chain · 50% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tryptophan synthase alpha chain | protein | 248 | 50% helix, 16% strand | Q8U094 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 255 | 0.67 | 0.83 | 38 | empty |
| 2 | 55 | 0.29 | 0.75 | 11 | empty |
Compared structures
- 1WDW · Structural basis of mutual activation of the tryptophan synthase A2B2 complex from a… · an experimental structure of the same protein · chain A against E, TM-score 0.97
- 1WDW · Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a… · an experimental structure of the same protein · chain A against E, TM-score 0.97
- 1GEQ · Entropic stabilization of the tryptophan synthase a-subunit from a hyperthermophile… · an experimental structure of the same protein · chain A against B, TM-score 0.97
- 1GEQ · Entropic stabilization of the tryptophan synthase A-subunit from a hyperthermophile… · an experimental structure of the same protein · chain A against B, TM-score 0.97
- 5E0K · X-ray crystal structure of tryptophan synthase complex from pyrococcus furiosus at 2.76 a · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 5E0K · X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 2DZS · Structure of mutant tryptophan synthase alpha-subunit (E103A) from a hyperthermophile… · an experimental structure of the same protein · chain A against B, TM-score 0.97
- 2DZS · Structure of mutant tryptophan synthase alpha-subunit (E103A) from a hyperthermophile… · an experimental structure of the same protein · chain A against B, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8U094
- Elsewhere: UniProt Q8U094 · AlphaFold DB Q8U094
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