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AlphaFold monomer V2.0 prediction for tRNA (ADENINE(58)-N(1))-methyltransferase catalytic subunit TRMT61A (Q96FX7)

Analyse AlphaFold monomer V2.0 prediction for tRNA (ADENINE(58)-N(1))-methyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q96FX7
Type
protein
Length
289 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
Molecule
TRNA (ADENINE(58)-N(1))-methyltransferase catalytic subunit TRMT61A
UniProt
Q96FX7
Pockets
1 · best druggability 0.50

Structure

1 distinct chain · 26% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATRNA (ADENINE(58)-N(1))-methyltransferase catalytic subunit TRMT61Aprotein28926% helix, 30% strandQ96FX7

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11390.500.7930empty

Compared structures

  • 5CCX · Structure of the product complex of tRNA m1A58 methyltransferase with tRNA3Lys as… · an experimental structure of the same protein · chain A against A, TM-score 0.95
  • 5CCX · Structure of the product complex of tRNA M1A58 methyltransferase with TRNA3LYS as… · an experimental structure of the same protein · chain A against A, TM-score 0.95
  • 5CCB · Crystal structure of human M1A58 methyltransferase in a complex with TRNA3LYS and sah · an experimental structure of the same protein · chain A against A, TM-score 0.95
  • 5CD1 · Structure of an asymmetric tetramer of human tRNA m1A58 methyltransferase in a complex… · an experimental structure of the same protein · chain A against D, TM-score 0.94
  • 5CD1 · Structure of an asymmetric tetramer of human tRNA M1A58 methyltransferase in a complex… · an experimental structure of the same protein · chain A against A, TM-score 0.94

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