UniProt Q96FX7
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (Q96FX7)
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (UniProt Q96FX7), EC 2.1.1.220: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and…
- UniProt
- Q96FX7
- Protein
- tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
- EC
- 2.1.1.220
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 2 records with a druggable one
Structures
6 records of Q96FX7 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CCB | Crystal structure of human M1A58 methyltransferase in a complex with TRNA3LYS and sah | x-ray diffraction | A | — | — |
| 5CCX | Structure of the product complex of tRNA m1A58 methyltransferase with tRNA3Lys as substrate | x-ray diffraction | A | — | — |
| 5CCX | Structure of the product complex of tRNA M1A58 methyltransferase with TRNA3LYS as substrate | x-ray diffraction | A | — | — |
| 5CD1 | Structure of an asymmetric tetramer of human tRNA m1A58 methyltransferase in a complex with SAH and… | x-ray diffraction | A, D | SAH | 13 (best 0.81) |
| 5CD1 | Structure of an asymmetric tetramer of human tRNA M1A58 methyltransferase in a complex with sah and… | x-ray diffraction | A, D | — | — |
| Q96FX7 | AlphaFold monomer V2.0 prediction for tRNA (ADENINE(58)-N(1))-methyltransferase catalytic subunit… | predicted | A | — | 1 (best 0.50) |
Ligands
- SAH · S-adenosyl-L-homocysteine · in 1 record
Experiment against prediction
- 5CD1 chain D against the predicted model Q96FX7: TM-score 0.97, RMSD 1.25 Å
- 5CD1 chain A against the predicted model Q96FX7: TM-score 0.97, RMSD 1.30 Å
- 5CCB chain A against the predicted model Q96FX7: TM-score 0.97, RMSD 1.28 Å
- 5CCX chain A against the predicted model Q96FX7: TM-score 0.96, RMSD 1.31 Å
- 5CCX chain A against the predicted model Q96FX7: TM-score 0.96, RMSD 1.31 Å
- 5CD1 chain A against the predicted model Q96FX7: TM-score 0.96, RMSD 1.30 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.