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AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM39 (Q9HCM9)

Analyse AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM39… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9HCM9
Type
protein
Length
518 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x0D671490EE06E75975e90D7F99F73B20BE618744
Molecule
E3 ubiquitin-protein ligase TRIM39
UniProt
Q9HCM9
Pockets
4 · best druggability 0.55

Structure

1 distinct chain · 42% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AE3 ubiquitin-protein ligase TRIM39protein51842% helix, 19% strandQ9HCM9

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11580.550.8025empty
21590.500.7817empty
3500.380.8012empty
4700.360.7713empty

Compared structures

  • 2DID · One sequence two fold ? : Correct fold of the zf-B-box domain from human tripartite motif… · an experimental structure of the same protein · chain A against A, TM-score 0.09
  • 2DID · One sequence two fold ? : correct fold of the zf-B-box domain from human tripartite motif… · an experimental structure of the same protein · chain A against A, TM-score 0.09
  • 2DIF · One sequence two fold ? : Miss fold of the zf-B-box domain from human tripartite motif… · an experimental structure of the same protein · chain A against A, TM-score 0.08
  • 2DIF · One sequence two fold ? : miss fold of the zf-B-box domain from human tripartite motif… · an experimental structure of the same protein · chain A against A, TM-score 0.08
  • 2ECJ · Solution structure of the RING domain of the human tripartite motif-containing protein 39 · an experimental structure of the same protein · chain A against A, TM-score 0.08
  • 2ECJ · Solution structure of the ring domain of the human tripartite motif- containing protein 39 · an experimental structure of the same protein · chain A against A, TM-score 0.08

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